Patterson had been out since the final week of Spring Training, after getting hit in the head by a fastball from Boston's Daniel Bard.
The 31-year-old Patterson is expected to join the Blue Jays in Seattle on Monday for the start of their three-game series against the Mariners.
To make room on the 25-man active roster, Toronto optioned right-hander Scott Richmond to Triple-A Las Vegas.
Richmond's first stint with the Blue Jays this season didn't last very long. He joined the team on Sunday morning, when utilityman Mike McCoy was optioned to the Minor Leagues.
Richmond was called up just for one game to provide emergency depth to an undermanned bullpen, following Saturday night's 14-inning game. Toronto's bullpen used six relievers, who threw a combined 8 2/3 innings in that game.
Thanks in part to an impressive performance by starting pitcher Jo-Jo Reyes, Toronto didn't need to get much out of Richmond. He retired the only batter he faced in the bottom of the eighth inning.
"As much as our bullpen has been pressed into duty -- and 14 innings last night, quick turnaround -- Scott is someone that we can budget for 70 pitches today, if needed," Blue Jays manager John Farrell said before Sunday's series finale against the Angels.
Patterson is expected to take over starting duties in center field for the next few days, after Rajai Davis re-aggravated his right ankle injury.
The native of Atlanta has hit .253, with 112 home runs and 205 stolen bases, during his 11-year career.