Ledezma was brought out to start the ninth inning in a 6-0 game but struggled to get through the frame. He was charged with six runs on five hits and three walks while throwing just 21 of his 45 pitches for strikes.
Toronto, which was faced with a lot of tired arms in the bullpen, had no other choice but to stick with Ledezma through the rough outing.
"No one wants to have to go through that," Blue Jays acting manager Don Wakamatsu said. "But we talked about three starts in a row not getting into the sixth and the bullpen being overworked. Once we fell behind 6-0 we tried to piece it together and get through that ballgame."
Ledezma, who spent most of the year in Triple-A Las Vegas, appeared in just five games for the Blue Jays. He posted a 15.00 ERA in six innings and noticeably struggled with his control, issuing seven walks.
The 30-year-old is 15-25 with a 5.40 ERA in 192 career appearances in the Major Leagues. Toronto will make a corresponding roster prior to Monday night's series finale against the Rays to complete its 25-man roster.