Edwin Encarnacion, Yunel Escobar and Jeff Mathis were held out for various reasons. All three players were originally listed on the lineup card, but they were then removed less than two hours prior to first pitch.
Encarnacion was held out of the lineup because of a sore big toe on his right foot. He aggravated the injury while running to third base during Saturday's 3-2 loss to Boston.
The toe issue isn't expected to linger, and following an off-day on Monday, it's likely that Encarnacion will be back in the lineup for Tuesday's series opener in New York. His absence comes just two days after he was forced to miss one game because of a sore left wrist.
Escobar and Mathis were both scratched because of flu-like symptoms. The flu bug has been going around the Blue Jays' clubhouse in recent weeks, and the pair has become the latest casualties. They're both expected to be ready for action on Tuesday against the Yankees.
Second baseman Kelly Johnson was inserted into the lineup while Adeiny Hechavarria moved over to shortstop to fill the void left behind by Escobar. J.P. Arencibia then got the start behind the plate for Mathis, while Yan Gomes received a rare opportunity at designated hitter.