Cabrera sat out a pair of games in Oakland this week because he was unable to cover ground in left, and even after he got back into the starting lineup Thursday it became evident that he's not capable of playing quality defense.
"His knee flared up," Blue Jays manager John Gibbons said after the Blue Jays' 8-2 loss to the Angels. "He'll go on the DL and get an MRI tomorrow. It's probably similar to what he had last time."
Cabrera's lack of range proved problematic during the Angels' first at-bat. Kole Calhoun lifted a fly ball to left field that most outfielders would have been able to track down, but Cabrera couldn't come up with it.
The 28-year-old had further difficulties in the third inning when his attempted throw back into the infield slipped out of his hand and allowed Mark Trumbo to score all the way from first base.
A timetable for his return wasn't immediately clear.
Right-hander Neil Wagner was recalled from Triple-A Buffalo to take Cabrera's spot on the 25-man roster. Wagner became a favorite of Gibbons earlier this season when he posted a 3.26 ERA in 19 1/3 innings before Cabrera's previous return from the DL forced his demotion to the Minors.
Gregor Chisholm is a reporter for MLB.com. Read his blog, North of the Border, and follow him on Twitter @gregorMLB. This story was not subject to the approval of Major League Baseball or its clubs.