The 31-year-old was at first base and the plan is for that to happen again on Wednesday while Adam Lind becomes a late-inning pinch-hitter off the bench.
"We'll see how it goes, I don't think it will be a big deal," Blue Jays manager John Gibbons said. "We need him."
Encarnacion missed approximately six weeks because of the quad injury, but it hasn't taken him very long to get his timing back at the plate. The Dominican native had a pair of hits during his recent three-game series vs. the White Sox, which included a two-run homer in Sunday's 7-5 loss.
Gregor Chisholm is a reporter for MLB.com. Read his blog, North of the Border, and follow him on Twitter @gregorMLB. This story was not subject to the approval of Major League Baseball or its clubs.